Charité Research Organisation has conducted multiple classical renal impairment studies. These are typical studies comparing safety, tolerability and pharmacokinetics in mild, moderate, severe and ESRD patients along with healthy controls.
CRO benefits from collaboration with the Charité Departments of Nephrology and other specialist dialysis units. These collaborations allow CRO to undertake early phase studies that require patients to be actively undergoing dialysis during the study and potentially during dosing where experimental dialysis approaches can be evaluated.
In addition to work in renal impaired populations, CRO is also able to undertake studies in specific populations, such as patients suffering from diabetic nephropathy.